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br Immunohistochemistry br At the end of
2019-10-14
2.9. Immunohistochemistry At the end of each animal study, the tumor tissues were collected from the mice and fixed with 10% (v/v) neutral buffered formalin, and then embedded in paraffin. The paraffin sections were deparaffinized in xylene, rehydrated in a series of graded alcohols and treated with 0
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br Generate new OGA SVM generation
2019-10-14
10. Generate new OGA-SVM generation from combining chromo-somes in k, h, w, e. 11. Replace old generation with the new generation contained all Dexmedetomidine produced from elitism, crossover, and mutation algorithms. The parameters used in Nested-GA are described in Table 2. Fig. 4. Cro
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br Microarrays are one of the well established tools used
2019-10-14
Microarrays are one of the well-established tools used to iden-tify and analyze the biological data. One function of the Microar-ray experiments is to monitor the Solasodine level of genes on the genome scale (Whitworth, 2010). Results of those experiments could be formed in a matrix, called Gene
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br METHOD DETAILS br In vitro and in vivo experimental
2019-10-14
METHOD DETAILS In vitro and in vivo experimental strategies Tissue dissociation, cell isolation, and FACS analysis Mouse pancreatic tumors were washed in MEM (GIBCO, Life Technologies) and cut into 1-2 mm pieces immediately following resec-tion. Tumor pieces were collected into a 50 mL Fa
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br MATERIALS AND METHODS br Study Population br This Health
2019-10-14
MATERIALS AND METHODS Study Population This Health Insurance Portability and Accountability Act-compliant retrospective evaluation of prospectively acquired data was approved by local ethics committee. Written informed consent was given by all patients. Flow diagram illustrating patient excl
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br read br RPM the reads per million
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read RPM the reads per million Appendix B. Supplementary data References [3] A.E. Pasquinelli, NON-CODING RNA MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship, Nat. Rev. Genet. 13 (2012) 271–282. N. Soga, S. Takahashi, Y. Kondo, Histone de
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br Patients were tested by
2019-10-08
Patients were tested by appropriate routine diagnostic pro-cesses to detect any mutation in highly penetrant genes, namely, BRCA1 or BRCA2 cancer predisposition CH 223191 routinely from 2009 Please cite this article as: Szollar A et al., A long-term retrospective comparative study of the oncol
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br ECT YAP cells were generated
2019-10-08
ECT1-YAP cells were generated by transfecting hCerEC and ECT1 cells with vectors expressing wild-type of YAP1 protein; hCerEC-YAPS127A and ECT1-YAPS127A cells were generated by transfecting hCerEC and ECT1 cells with vectors expressing constitutively active YAP1 (YAPS127A, Serine at residue 127 i
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Minocycline HCl br every gene annotation br annotation
2019-10-07
every gene annotation annotation annotation gene copy- fusion and and number breakpoint COSMIC query COSMIC query variation rebuilding get clinically relevant information final clinical report Abbreviations: CNA ¼ copy number alteration; COSMIC ¼ Catalogue Of Somatic Mu
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br Conclusions br Appropriate feature selection is required
2019-09-28
5. Conclusions Appropriate feature selection is required when building a col-orectal cancer risk prediction model. It helps to avoid overfit-ting and is an aid to identify the features with more prediction power so that proper interventions can be taken to address the risk.Assessing the stabili
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br Lastly the bPEI MGO was decorated
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Lastly, the bPEI-MGO was decorated with PB nanoparticles to ex-hibit excellent peroxidase activity. The synthesis process was as follows: 10 mL of PB precursor solution that contained 5 mM of FeCl3 and 5 mM of K3[Fe(CN)6] was prepared. After the pH value was adjusted to 1.5, the solution was mixed
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br To show that p has an essential role
2019-09-23
To show that p53 has an essential role in response to 8-AHN treatment, RNAi studies were carried out to knock down endogenous p53 expression using TP53-specific siRNA. FCM showed that silencing of p53 by siRNA can partially rescue cells from 8-AHN-induced cell apoptosis (Fig. 5C). Summarized these
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br To search for additional
2019-09-23
To search for additional HR gene mutations, DNA from HR-deficient cases that lacked deleterious BRCA1 or BRCA2 mutations was isolated from FFPE slides by laser capture microdissection and assayed for muta-tions in genes involved in DNA repair (Table S1) by BROCA-HR DNA se-quencing as previously de
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br was incorporated in the training folds there was
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was incorporated in the training folds, there was no sin-gle multi-parameter set. However, as depicted in Figure 5a, the selection of the parameters clearly favored a specific order of combination. Ultimately, only the GMM and SVM with combinations of respectively three and eight parameters were i
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br This study is a large population based study
2019-09-16
This study is a large, population-based study to evaluate RS use, categorize RS distribution and evaluate factors associated with high-risk scores and survival in the older women with breast cancer. However, there are inherent limitations which must be considered. As a retrospective study, it is s