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br Data were screened for missing responses which
2020-07-04
Data were screened for missing responses, which amounted to less than 5% overall and were typically due to insufficient saliva amounts. The expectation-maximization (EM) algorithm was used to impute missing values when participants had no more than two missing data points (out of 10) for diurnal Lyc
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br Table Adverse effects of immune checkpoint
2020-07-04
Table 3. Adverse effects of immune checkpoint therapy reported by ED patients with cancer. Adverse Effect Ipilimumab Nivolumab Pembrolizumab >1 Medication Myocarditis Eye effects We investigated whether any of the identified immune-related adverse effects were associated with survival
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br caption on next page br Fig CDK
2020-03-24
(caption on next page) Fig. 1. CDK1 is activated in vemurafenib-resistant colon cancer. (A) IPA analysis suggested significant changes in the expression of Tadalafil checkpoint proteins, including CDK1 signaling, in colon cancer cells treated with PLX4720, an analog of vemurafenib (GSE50791). (
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br Detection of LC II LC I by western blot
2020-03-24
2.6.2.4. Detection of LC3-II/LC3-I by western-blot. This experiment was carried out according to previous report32. Briefly, cell lysates were extracted by using sodium dodecyl sulfate-PAGE and transferred to a PVDF membrane. Then, it was incubated overnight with primary antibody against LC3B (rab
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Acarbose br Recently a retrospective pooled
2020-03-17
Recently, a retrospective pooled analysis of 2 prematurely terminated randomized controlled trials suggested that SBRT is better tolerated than surgery and may lead to improved overall survival.7 However, several study limitations necessitate caution to avoid over-interpreting these results, and t
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br Appendix A Supplementary data br References br
2020-03-17
Appendix A. Supplementary data References Antaki, P.J., 2005. New interpretation of Non-Fourier heat conduction in processed meat. Budman, H., Shitzer, A., Dayan, J., 1995. Analysis of the inverse problem of freezing and thawing of a binary solution durin cryosurgical processes. J. Biomec
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br M Mirrahimi et al br nanocomposites that integrate variou
2020-03-17
M. Mirrahimi, et al. nanocomposites that integrate various therapeutic functions into a single platform have recently attracted increasing interest for simulta-neous delivery of multiple treatments to the tumor [7]. Recently, gold nanoparticles (AuNPs) have been widely considered as one of t
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br Some very significantly altered serum proteins in univari
2020-03-17
Some very significantly altered serum EPZ031686 in univariate analy-sis, such as GCNT1 and NTRK3, were not selected in the regression model, presumably due to the collinearity of the proteins with others. Conflicting results between univariate analysis and multivariate logis-tic regression is not
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br Each super category was
2019-11-11
Each super category was further broken down into the concerns that comprise each super category. For the breast cancer group, these included: S1e: Emotional problems S1g: Fear and anxiety Figure 6 Change in MYCaW Score (A), Well-being (B), and Total Concerns (C) for Patients With Breast C
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br Fig Somatic gene sequences and
2019-10-29
Fig. 3. Somatic gene sequences and its similarity measures. Fig. 4. Somatic gene sequences and its runtime (ms) computation for different mappers. T. Bikku and R. Paturi (2) Starting from the elimination of suffix elimination and producing the word stems comes under Stemming [24]. Adding
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br Combination Index analysis br IC concentrations were dete
2019-10-24
2.8. Combination Index analysis IC50 concentrations were determined for rutin and fucoidan upon incubation of HeLa and HaCaT cell lines with multiple doses of each compound (Table 1). Combination index (CI) was calculated for the mixture of two compounds based on the previous study [30]. The va
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On the other hand free PTX and PLGA PTX
2019-10-22
On the other hand, free PTX and PLGA-PTX NPs showed a dose-dependent response in all cell lines tested. However, the cytotoxicity was significantly higher when PTX was loaded within PLGA NPs com-pared with free PTX (p Fig. 1. Characterization of the PTX-loaded NPs. A, Scanning electron microscope
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br For the comparison among di erent NCs
2019-10-22
For the comparison among different NCs, all NCs formulations at a concentration of 4% w/v were formulated with a 2% w/v gelator concentration. 2.2.4.1. Measurement of storage and loss modulus. Oscillatory rheology was carried out using an Anton Paar MCR302 Modular Compact Rheometer using a cu
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br The capacity of an ADS
2019-10-16
The capacity of an ADS Cy5-PEG-Protein/mAb to bind the target antigen expressed on the cell surface was then assessed by other ex-periments. mAbs were added to Cy5-PEG5kDa-SpA or Cy5-PEG20kDa-SpG PBS solutions at the binding stoichiometry determined by ITC analysis as follows: a 1.6-fold molar exc
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br Considering that the undifferentiated CSCs are more
2019-10-15
Considering that the undifferentiated CSCs are more resistant to chemotherapy and apoptosis than differentiated cancer cells, the pre-sent study initially used flow cytometry to detect the percentage of CD44+/CD24− cells in DSCs following treatment with different che-motherapies. Subsequently, the