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br Fig Blockade of TGF
2020-08-30
Fig. 7. Blockade of TGF-βRI reduces CD73 expression in CeCa cells. CaSki (A) and HeLa (B) Nivolumab (1 × 105) were cultured with 1 mM Ado in the presence or absence of 25 μM SB505124, selective inhibitor of TGF-β type I receptors. After 96 h, CD73 expression on the cell membrane was analyzed by fl
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br Conflict of interest br None br Authors
2020-08-30
Conflict of interest None. Authors contribution AT (Corresponding author): conceived Sincalide and research ob-jectives, designed and performed experiments, gathered and analyzed data, drafted and critically revised the manuscript, and approved the final version. KKM (Contributor): desi
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br selected multivariable linear regression model was pre
2020-08-28
selected multivariable linear regression model was pre-sented. This analysis was done for the endpoints LVEF, GLS of the LV, and diastolic function, respectively. Data were analyzed using MATLAB (version R2017a) and SPSS (IBM SPSS Statistics, version 22, IBM Corp). Results Patient charact
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br Table br Estimated proportion and numbers of cancer cases
2020-08-28
Table 2 Estimated proportion (%) and numbers of cancer cases attributable to insufficient physical activity in France in 2015, by sex, cancer site and reference. Men Women Both sexes Breast (postmenopausal) Colon Breast (postmenopausal) Breast (postmenopausal) a Proporti
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b iframe width height src https www
2020-08-28
r> Given the varied mechanisms that are instrumental in specifying the drug resistant and metastatic properties of the cancer stem cells, es-tablishment of a marker panel that can define these properties will help to develop a predictive biomarker panel of clinical significance. Subject to large sc
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br We restricted the mortality
2020-08-28
We restricted the mortality analysis timeframe to 2001–2011, which reduced the total number of deaths from 847 deaths, confirmed through death records search (1988–2011), to 526 deaths. We confirmed through death records that one mesothelioma, one cancer of the pleura, and two asbestosis deaths oc
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br The aim of this exploratory
2020-08-24
The aim of this exploratory study was to provide initial infor-mation about the knowledge of BC and its screening practices among Yemeni women attending PHCCs in Ghail Bawazir, Hadhramout Province. Table 7 Barriers to Practicing BSE, CBE, and Mammogram and the Use of BC Screening Methods BSE
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Redox Biology br that the expression of BPTF was
2020-08-18
Redox Biology 20 (2019) 427–441 that the expression of BPTF was higher in cirrhosis, hepatocellular carcinoma, liver cell dysplasia than in normal tissues, and was the highest in HCC samples (Fig. 1C). Consistently, TCGA data also showed that the BPTF DNA copy number in HCC samples were greatl
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br ADT treated men were
2020-08-18
ADT-treated men were recruited between April 2014 and November 2017 via clinician referral from Alfred Health (Melbourne, Australia), Peter MacCallum Cancer Centre (Victoria, Australia) and six private urology practices (Victoria, Australia), as well as from 32 PCa support groups (Victoria, Austra
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br Introduction br Pain is frequently the first clinical sym
2020-08-18
1. Introduction Pain is frequently the first clinical symptom of head and neck car-cinoma. Indeed, pain is the initial reason leading ∼70% of cancer pa-tients to seek professional assistance (Lam & Schmidt, 2011; Rettig & D’Souza, 2015; Schmidt, 2014). Clinically, cancer-induced facial pain can
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4-Phenylbutyric acid br Activation of ERK is involved in BPS
2020-08-18
3.6. Activation of ERK1/2 is involved in BPS induced activation of TGF-β/ Smad2/3 signal It has been reported that activation of ERK1/2, JNK, and p38-MAPK can regulate the transcription of TGF-β in cancer 4-Phenylbutyric acid (Xiao et al., 2008). We pre-treated A549 and H1299 cells with the in
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br Fig Transmission electron microscopy
2020-08-18
Fig. 2. Transmission electron microscopy (TEM) images (A, B), field emission scanning electron microscopy (FESEM) images (C) and selected-area electron dif-fraction (SAED) patterns (D) of CuO NPs. Fig. 3. Energy-dispersive X-ray spectroscopy (EDS) spectrum of biosynthesized CuO NPs. aptamer-
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br P compared to corresponding control or
2020-08-18
***P < 0.001, compared to corresponding control (1- or 2-way ANOVA). (E) Immunoblot analyses showed that ARID3B protein levels were elevated in PANC-1 and AsPC-1 cells after transfection with bioengineered miR-1291. Both the full-length ARID3B (ARID3B-Fl, ∼61 kD) and the short-form ARID3B (ARID3B-
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br Introduction br Recently paclitaxel PTX preparations whic
2020-08-18
1. Introduction Recently, paclitaxel (PTX) preparations, which are effective for the treatment of various tumors such as breast cancer, non-small cell lung cancer, and ovarian cancer have been widely used and studied [1,2]. This anticancer agent exerts a tumor effect by polymerizing tubulin monom
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br Quantification of apoptosis and
2020-08-18
Quantification of apoptosis and the cell cycle was performed on a FACSCalibur Flow Cytometer (Becton Dickinson, USA), as described [31]. NETs-treated and untreated cancer cells were harvested, treated with 20 μg/mL of RNase A and 50 μg/mL of PI (R4642-10MG, 81845-25MG, Sigma-Aldrich) after fixatio